Published on Jun 30, 2023 | 2:48 PM
Share Article :
Having been irradicated throughout the states between 1947 to 1951 by what would later be the CDC, malaria is still an entirely rare disease in the United States. (1) However, recently, a very small number of cases have appeared in Texas and Florida, the first local infections since 2003. Despite being extremely rare, it is important to understand more about malaria and ways you can take precautions.
Caused by parasites of the Plasmodium species, malaria can be a deadly disease due to the severe complications it can cause. Coming in multiple types, the most common forms are Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, and Plasmodium ovale. The specific type found recently in Texas and Florida was Plasmodium vivax or P. Vivax, which is considered less severe compared to the other variations. (2)
Primarily spread through infected mosquitos, each version of malaria can also be passed on through the sharing of needles, blood transfusion, and organ transplants. Each vector causes infection due to the Plasmodium parasites gaining entry into the human bloodstream. (3)
While cases have been identified in Florida and Texas, the Center for Disease Control has stated the chances of catching malaria are still “extremely low.” (4) In the instances that it does occur in the states, those that have managed to catch it are typically traveling back from tropical regions of the world, more generally, from Africa, South Asia, and South America. Such cases are known as “airport” malaria, which is when an infected mosquito infects a person before they get on the flight or when the mosquito is transported to the States and bites someone locally. (5)
In the case that the disease is locally transmitted, it is due to the mosquito escaping the airport environment and finding an environment where it can reproduce. States like Texas and Florida have regions that are well suited for mosquitos, such as swamps and forests, where standing water is able to remain undisturbed long enough for mosquitoes to age to maturity.
In the first month after catching the disease, those that are infected with malaria won’t feel anything as it needs time to develop. Once symptoms do appear after the incubation period, they often include recurrent episodes of fever, chills, sweating, headache, fatigue, muscle and joint pain, and sometimes nausea and vomiting. These symptoms can occur in cycles, with symptoms improving and then returning periodically. The characteristic pattern of P. vivax malaria involves relapses, where the infection reactivates from dormant forms (hypnozoites) in the liver, leading to recurrent episodes of malaria over an extended period of time.
While the frequency and severity of these relapses can vary among individuals, leaving malaria untreated will result in worse symptoms. Descriptively, fever spikes may occur every 48 hours, giving a characteristic pattern of recurring seizures. Along with fever, other symptoms may persist or intensify. (6)
It's important to note that the type of malaria that has been recently appearing in Texas and Florida (P. vivax), is one form with potential for relapse if left untreated, unlike the other types of malaria. Hypnozoites, dormant forms of the parasite, can remain in the liver and reactivate later, causing recurrent malaria episodes. These relapses may occur weeks, months, or even years after the initial infection, leading to periods of recurring symptoms.
If a doctor suspects malaria in a patient before conducting any tests, they will typically take several steps to evaluate the situation. They will gather a detailed medical history, focusing on the patient's travel history to malaria-endemic areas and potential exposure to malaria. They will also perform a thorough physical examination, looking for signs and symptoms commonly associated with malaria. When the disease is suspected, the following tests can be performed:
Malaria is treated using antimalarial medications, which aim to eliminate the Plasmodium parasites causing the infection. The specific choice of medication and treatment regimen depends on factors such as the type of malaria parasite. In the case of Plasmodium vivax, the treatment regimen will include oral antimalarial prescriptions that generally are to be taken for two weeks, such as chloroquine and Atovaquone-proguanil.
Chloroquine is effective against Plasmodium vivax because it targets the parasite's lifecycle within the red blood cells. It is a blood schizonticide, meaning it acts on the asexual stage of the parasite's life cycle when it replicates inside the red blood cells. It works by interfering with the parasite's ability to break down hemoglobin, preventing it from obtaining the nutrients it needs to survive and reproduce.
Atovaquone-proguanil, also known as Malarone, is effective against Plasmodium vivax due to its dual mechanism of action and broad-spectrum antimalarial activity. The combination of atovaquone and proguanil in this medication targets different stages of the parasite's life cycle, making it effective against both the liver-stage and blood-stage forms of Plasmodium vivax.
While there are other options that doctors can prescribe, these two medications have proven to be the most effective. Additionally, a doctor will also suggest fever management, plenty of fluids, and bed rest. More severe cases may require professional monitoring of the patient, but such instances are incredibly rare in the United States.
Effective treatment can help clear the malaria infection, alleviate symptoms, and prevent complications. It is crucial to diagnose and treat malaria promptly to prevent the progression of the disease and potentially life-threatening complications associated with severe malaria.
Malaria can be prevented through a combination of interventions aimed at reducing the transmission of the malaria parasite. These measures include vector control strategies to target the mosquitoes that transmit the disease, as well as personal protective measures. Vector control involves using insecticide-treated bed nets, indoor residual spraying with insecticides, and environmental management to eliminate mosquito breeding sites.
Personal protective measures include wearing protective clothing, using insect repellents, and taking antimalarial medications when traveling to regions with a high malaria risk. Early diagnosis and prompt treatment of malaria cases also contribute to preventing the further spread of the disease.
While still rare in the United States, educating yourself about malaria transmission will help you also combat many other diseases like it. As the main mode of transmission, managing and avoiding mosquitos in your personal environment is crucial, and learning how to do so is your best chance of staying healthy even when in an area where the disease is more common.
English graduate and Call-On-Doc’s medical resource guide, Wayne C. Hahne is an experienced and passionate medical education content expert. Through diligent research, provider interviews and utilizing the industry's leading resources for wellness information, it is Mr. Hahne’s personal mission to educate the general public on medical conditions with in-depth and easy-to-understand written guides.
Understanding Amoxicillin Skin Rash: Causes, Symptoms, and What to Do
Amoxicillin is one of the most commonly prescribed antibiotics for bacterial infections. Its effectiveness and versatility make it a go-to choice for many healthcare providers. However, like all medications, it can have side effects, one of which is the development of a rash.
If you’ve experienced a rash while taking amoxicillin, you might wonder whether it’s an allergic reaction or a different kind of response. Below, we’ll explore what amoxicillin skin rash is, how to identify it, and the steps you should take if you develop one.
Dec 08, 2024 | 10:10 AM
How to Get Rid of a UTI Fast
Urinary tract infections (UTIs) are one of the most common infections, affecting millions of people each year. When a UTI strikes, the symptoms can be both uncomfortable and disruptive, and without prompt treatment, they can quickly worsen.
Whether you’re experiencing a UTI for the first time or you’re prone to frequent infections, knowing how to recognize and address a UTI early is key to a fast and smooth recovery. This guide covers effective steps to treat a UTI quickly and prevent it from coming back.
Nov 20, 2024 | 10:10 AM
Chlamydia vs Gonorrhea vs Trichomoniasis
Sexually transmitted infections (STIs) are more common than you might think, affecting millions of people every year. They’re usually spread through sexual contact, but some can also be passed from a mother to her baby during childbirth or through blood.
STIs, like chlamydia, gonorrhea, and trichomoniasis, often share similar symptoms—things like unusual discharge, pain when you pee, or itching. This makes it difficult to tell which one you might have just based on symptoms alone. While a doctor is your best resource for accurate guidance, we’ll break down the main differences between chlamydia, gonorrhea, and trichomoniasis in the sections below.
Sep 12, 2024 | 10:10 AM
Understanding Amoxicillin Skin Rash: Causes, Symptoms, and What to Do
Amoxicillin is one of the most commonly prescribed antibiotics for bacterial infections. Its effectiveness and versatility make it a go-to choice for many healthcare providers. However, like all medications, it can have side effects, one of which is the development of a rash.
If you’ve experienced a rash while taking amoxicillin, you might wonder whether it’s an allergic reaction or a different kind of response. Below, we’ll explore what amoxicillin skin rash is, how to identify it, and the steps you should take if you develop one.
Dec 08, 2024 | 10:10 AM
How to Get Rid of a UTI Fast
Urinary tract infections (UTIs) are one of the most common infections, affecting millions of people each year. When a UTI strikes, the symptoms can be both uncomfortable and disruptive, and without prompt treatment, they can quickly worsen.
Whether you’re experiencing a UTI for the first time or you’re prone to frequent infections, knowing how to recognize and address a UTI early is key to a fast and smooth recovery. This guide covers effective steps to treat a UTI quickly and prevent it from coming back.
Nov 20, 2024 | 10:10 AM
Chlamydia vs Gonorrhea vs Trichomoniasis
Sexually transmitted infections (STIs) are more common than you might think, affecting millions of people every year. They’re usually spread through sexual contact, but some can also be passed from a mother to her baby during childbirth or through blood.
STIs, like chlamydia, gonorrhea, and trichomoniasis, often share similar symptoms—things like unusual discharge, pain when you pee, or itching. This makes it difficult to tell which one you might have just based on symptoms alone. While a doctor is your best resource for accurate guidance, we’ll break down the main differences between chlamydia, gonorrhea, and trichomoniasis in the sections below.
Sep 12, 2024 | 10:10 AM
Feedback from our amazing patients!
"I can’t believe I did not know about this kind of service! This was absolutely perfect for my health concern and they were able to provide me with the necessary medication and with such cinch. Completely recommended this service. For minor health concerns, this can save you an unnecessary and costly trip to an urgent care center."
"Amazing!! Easy and fast! I didn’t have to take my 4 year old into an urgent care where only god knows what germs are there. The doctor sent the script right to my pharmacy within minutes!!!"
"I would give 10 stars if I could! CallonDoc is literally the reason I am recovering instead of suffering as I write this. I was skeptical at first, but I’m not kidding when I tell you I got prescribed my antibiotics and picked it up at the pharmacy within 2 hours. So instead of waiting & paying around 300$...I paid 40$!! I’m very pleased."
Be the first to know when we offer deals.
Want to learn about a specific topic or condition?